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報告題目: Old Unsolved Problems in Biology and New Computational Perspectives from Topology and Statistical Learning Theory: From Bacteria and Plants towards the Human Brain
時間: 1.18(星期日) 下午2:00
地點: 研究生樓306
主講人介紹:Amir Assadi教授于于加州大學(xué)伯克利分校獲得數(shù)學(xué)學(xué)士學(xué)位(1974),于普林斯頓大學(xué)獲得數(shù)學(xué)碩士學(xué)位(1975)并在1979年獲得博士學(xué)位(微分拓撲方向),。Assadi教授先后在普林斯頓大學(xué)、弗吉尼亞大學(xué)以及威斯康星大學(xué)任教,,自1990至今為威斯康星大學(xué)麥迪遜分校教授,,并兼職于生物醫(yī)學(xué)工程系、設(shè)計學(xué)院,、醫(yī)學(xué)和公共衛(wèi)生學(xué)院,、生物技術(shù)中心等機構(gòu)。Assadi教授的研究方向包括:1.純數(shù)學(xué):微分拓撲,、微分幾何,;2.應(yīng)用數(shù)學(xué):信息科學(xué)、反問題,、大數(shù)據(jù)研究、超級計算信息學(xué),;3.跨領(lǐng)域研究:信息神經(jīng)學(xué),、視覺圖像科學(xué)、生物信息理論,、系統(tǒng)生物學(xué),。
報告主要內(nèi)容:Study of variation in observable biological features (morphological variations, phenotypic traits) in an organism (species) is an old area of biology. Darwin uses "variation" as a cornerstone of his theory of evolution. In this expository lecture, I discuss examples morphological variation in diverse contexts. Then I provide unifying mathematical interpretations of certain concrete biological questions. Using contemporary understanding of molecular networks and their dynamics, I propose rigorous computational approaches to verify the mathematical conjectures and to test the related biological hypotheses regarding morphological variations and quantifying phenotypic traits.